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Major League Soccer Betting Overview

96 Total Items 96 Predictions

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Betting on Major League Soccer requires understanding its conference format and playoff system. The league’s parity means underdogs often challenge favorites, affecting moneyline and spread markets. Games tend to be open, with high goal totals making over/under bets relevant. Home advantage is significant, but cross-country travel can level performance. Roster rules and summer transfers add complexity to team dynamics. For deeper analysis on specific matchups and trends, visit our preview pages.

Predictions

96 items

Toronto FC FC Cincinnati

American Major League Soccer

2026-04-11T17:00:00+00:00

Over/Under Goals

Toronto FC FC Cincinnati

New England Revolution DC United

American Major League Soccer

2026-04-11T23:30:00+00:00

Over/Under Goals

New England Revolution DC United

Vancouver Whitecaps New York City FC

American Major League Soccer

2026-04-11T23:30:00+00:00

Over/Under Goals

Vancouver Whitecaps New York City FC

Inter Miami New York Red Bulls

American Major League Soccer

2026-04-11T23:30:00+00:00

Both Teams to Score

Inter Miami New York Red Bulls

Portland Timbers Los Angeles FC

American Major League Soccer

2026-04-11T20:45:00+00:00

Over/Under Goals

Portland Timbers Los Angeles FC

CF Montréal Philadelphia Union

American Major League Soccer

2026-04-11T18:30:00+00:00

Over/Under Goals

CF Montréal Philadelphia Union

Austin FC LA Galaxy

American Major League Soccer

2026-04-11T18:30:00+00:00

Over/Under Goals

Austin FC LA Galaxy

Charlotte FC Nashville SC

American Major League Soccer

2026-04-11T23:30:00+00:00

Over/Under Goals

Charlotte FC Nashville SC

Houston Dynamo Seattle Sounders

American Major League Soccer

2026-04-05T00:30:00+00:00

Over/Under Goals

Houston Dynamo Seattle Sounders

San Jose Earthquakes San Diego FC

American Major League Soccer

2026-04-05T02:30:00+00:00

Moneyline (1X2)

San Jose Earthquakes San Diego FC

LA Galaxy Minnesota United

American Major League Soccer

2026-04-05T02:30:00+00:00

Over/Under Goals

LA Galaxy Minnesota United

Los Angeles FC Orlando City

American Major League Soccer

2026-04-05T01:30:00+00:00

Over/Under Goals

Los Angeles FC Orlando City

Chicago Fire Nashville SC

American Major League Soccer

2026-04-05T00:30:00+00:00

Both Teams to Score

Chicago Fire Nashville SC

Vancouver Whitecaps Portland Timbers

American Major League Soccer

2026-04-05T02:30:00+00:00

Over/Under Goals

Vancouver Whitecaps Portland Timbers

Atlanta United Columbus Crew

American Major League Soccer

2026-04-04T23:30:00+00:00

Both Teams to Score

Atlanta United Columbus Crew

Real Salt Lake Sporting Kansas City

American Major League Soccer

2026-04-04T20:30:00+00:00

Over/Under Goals

Real Salt Lake Sporting Kansas City

New York City FC St. Louis City SC

American Major League Soccer

2026-04-04T23:30:00+00:00

Over/Under Goals

New York City FC St. Louis City SC

Toronto FC Colorado Rapids

American Major League Soccer

2026-04-04T17:00:00+00:00

Both Teams to Score

Toronto FC Colorado Rapids

New York Red Bulls FC Cincinnati

American Major League Soccer

2026-04-04T23:30:00+00:00

Over/Under Goals

New York Red Bulls FC Cincinnati

Inter Miami Austin FC

American Major League Soccer

2026-04-04T23:30:00+00:00

Moneyline (1X2)

Inter Miami Austin FC

DC United FC Dallas

American Major League Soccer

2026-04-04T23:30:00+00:00

Over/Under Goals

DC United FC Dallas

New England Revolution CF Montréal

American Major League Soccer

2026-04-04T20:30:00+00:00

Over/Under Goals

New England Revolution CF Montréal

Charlotte FC Philadelphia Union

American Major League Soccer

2026-04-04T23:30:00+00:00

Over/Under Goals

Charlotte FC Philadelphia Union

FC Cincinnati CF Montréal

American Major League Soccer

2026-03-22T17:00:00+00:00

Over/Under Goals

FC Cincinnati CF Montréal

St. Louis City SC New England Revolution

American Major League Soccer

2026-03-22T00:30:00+00:00

Moneyline (1X2)

St. Louis City SC New England Revolution

Portland Timbers LA Galaxy

American Major League Soccer

2026-03-22T20:45:00+00:00

Over/Under Goals

Portland Timbers LA Galaxy

FC Dallas Houston Dynamo

American Major League Soccer

2026-03-22T00:30:00+00:00

Over/Under Goals

FC Dallas Houston Dynamo

Minnesota United Seattle Sounders

American Major League Soccer

2026-03-22T18:30:00+00:00

Over/Under Goals

Minnesota United Seattle Sounders

Austin FC Los Angeles FC

American Major League Soccer

2026-03-22T00:30:00+00:00

Moneyline (1X2)

Austin FC Los Angeles FC

New York City FC Inter Miami

American Major League Soccer

2026-03-22T17:00:00+00:00

Over/Under Goals

New York City FC Inter Miami

Vancouver Whitecaps San Jose Earthquakes

American Major League Soccer

2026-03-22T02:30:00+00:00

Moneyline (1X2)

Vancouver Whitecaps San Jose Earthquakes

San Diego FC Real Salt Lake

American Major League Soccer

2026-03-22T23:00:00+00:00

Over/Under Goals

San Diego FC Real Salt Lake

Sporting Kansas City Colorado Rapids

American Major League Soccer

2026-03-22T00:30:00+00:00

Over/Under Goals

Sporting Kansas City Colorado Rapids

Toronto FC Columbus Crew

American Major League Soccer

2026-03-21T17:00:00+00:00

Both Teams to Score

Toronto FC Columbus Crew

Atlanta United DC United

American Major League Soccer

2026-03-21T23:30:00+00:00

Over/Under Goals

Atlanta United DC United

Charlotte FC New York Red Bulls

American Major League Soccer

2026-03-21T23:30:00+00:00

Both Teams to Score

Charlotte FC New York Red Bulls

Nashville SC Orlando City

American Major League Soccer

2026-03-21T22:15:00+00:00

Both Teams to Score

Nashville SC Orlando City

Philadelphia Union Chicago Fire

American Major League Soccer

2026-03-21T20:30:00+00:00

Moneyline (1X2)

Philadelphia Union Chicago Fire

Real Salt Lake Austin FC

American Major League Soccer

2026-03-15T01:30:00+00:00

Moneyline (1X2)

Real Salt Lake Austin FC

Vancouver Whitecaps Minnesota United

American Major League Soccer

2026-03-15T02:30:00+00:00

Moneyline (1X2)

Vancouver Whitecaps Minnesota United

Houston Dynamo Portland Timbers

American Major League Soccer

2026-03-15T00:30:00+00:00

Over/Under Goals

Houston Dynamo Portland Timbers

New England Revolution FC Cincinnati

American Major League Soccer

2026-03-15T18:30:00+00:00

Both Teams to Score

New England Revolution FC Cincinnati

San Jose Earthquakes Seattle Sounders

American Major League Soccer

2026-03-15T23:00:00+00:00

Moneyline (1X2)

San Jose Earthquakes Seattle Sounders

LA Galaxy Sporting Kansas City

American Major League Soccer

2026-03-15T01:30:00+00:00

Moneyline (1X2)

LA Galaxy Sporting Kansas City

Chicago Fire DC United

American Major League Soccer

2026-03-15T00:30:00+00:00

Over/Under Goals

Chicago Fire DC United

FC Dallas San Diego FC

American Major League Soccer

2026-03-15T00:30:00+00:00

Over/Under Goals

FC Dallas San Diego FC

Los Angeles FC St. Louis City SC

American Major League Soccer

2026-03-15T02:30:00+00:00

Over/Under Goals

Los Angeles FC St. Louis City SC

New York City FC Colorado Rapids

American Major League Soccer

2026-03-14T23:30:00+00:00

Both Teams to Score

New York City FC Colorado Rapids

Orlando City CF Montréal

American Major League Soccer

2026-03-14T23:30:00+00:00

Over/Under Goals

Orlando City CF Montréal

Charlotte FC Inter Miami

American Major League Soccer

2026-03-14T23:30:00+00:00

Over/Under Goals

Charlotte FC Inter Miami

Columbus Crew Nashville SC

American Major League Soccer

2026-03-14T22:15:00+00:00

Both Teams to Score

Columbus Crew Nashville SC

Toronto FC New York Red Bulls

American Major League Soccer

2026-03-14T17:00:00+00:00

Over/Under Goals

Toronto FC New York Red Bulls

Atlanta United Philadelphia Union

American Major League Soccer

2026-03-14T19:15:00+00:00

Both Teams to Score

Atlanta United Philadelphia Union

Philadelphia Union San Jose Earthquakes

American Major League Soccer

2026-03-08T00:30:00+00:00

Moneyline (1X2)

Philadelphia Union San Jose Earthquakes

Columbus Crew Chicago Fire

American Major League Soccer

2026-03-08T00:30:00+00:00

Moneyline (1X2)

Columbus Crew Chicago Fire

Portland Timbers Vancouver Whitecaps

American Major League Soccer

2026-03-08T03:30:00+00:00

Over/Under Goals

Portland Timbers Vancouver Whitecaps

FC Cincinnati Toronto FC

American Major League Soccer

2026-03-08T23:00:00+00:00

Over/Under Goals

FC Cincinnati Toronto FC

New York Red Bulls CF Montréal

American Major League Soccer

2026-03-08T20:30:00+00:00

Over/Under Goals

New York Red Bulls CF Montréal

Colorado Rapids LA Galaxy

American Major League Soccer

2026-03-08T02:30:00+00:00

Over/Under Goals

Colorado Rapids LA Galaxy

Charlotte FC Austin FC

American Major League Soccer

2026-03-08T00:30:00+00:00

Moneyline

Charlotte FC Austin FC

Los Angeles FC FC Dallas

American Major League Soccer

2026-03-08T03:30:00+00:00

Over/Under Goals

Los Angeles FC FC Dallas

Sporting Kansas City San Diego FC

American Major League Soccer

2026-03-08T01:30:00+00:00

Over/Under Goals

Sporting Kansas City San Diego FC

Nashville SC Minnesota United

American Major League Soccer

2026-03-08T01:30:00+00:00

Over/Under Goals

Nashville SC Minnesota United

St. Louis City SC Seattle Sounders

American Major League Soccer

2026-03-08T01:30:00+00:00

Over/Under Goals

St. Louis City SC Seattle Sounders

Atlanta United Real Salt Lake

American Major League Soccer

2026-03-08T00:30:00+00:00

Both Teams to Score

Atlanta United Real Salt Lake

DC United Inter Miami

American Major League Soccer

2026-03-07T21:30:00+00:00

Over/Under Goals

DC United Inter Miami

New England Revolution Houston Dynamo

American Major League Soccer

2026-03-07T19:30:00+00:00

Over/Under Goals

New England Revolution Houston Dynamo

New York City FC Orlando City

American Major League Soccer

2026-03-07T19:30:00+00:00

Over/Under Goals

New York City FC Orlando City

San Diego FC St. Louis City SC

American Major League Soccer

2026-03-02T02:15:00+00:00

Over/Under Goals

San Diego FC St. Louis City SC

Orlando City Inter Miami

American Major League Soccer

2026-03-02T00:00:00+00:00

Both Teams to Score

Orlando City Inter Miami

Sporting Kansas City Columbus Crew

American Major League Soccer

2026-03-01T01:30:00+00:00

Over/Under Goals

Sporting Kansas City Columbus Crew

San Jose Earthquakes Atlanta United

American Major League Soccer

2026-03-01T00:30:00+00:00

Moneyline (1X2)

San Jose Earthquakes Atlanta United

Philadelphia Union New York City FC

American Major League Soccer

2026-03-01T21:30:00+00:00

Over/Under Goals

Philadelphia Union New York City FC

LA Galaxy Charlotte FC

American Major League Soccer

2026-03-01T03:30:00+00:00

Over/Under Goals

LA Galaxy Charlotte FC

Vancouver Whitecaps Toronto FC

American Major League Soccer

2026-03-01T02:30:00+00:00

Both Teams to Score

Vancouver Whitecaps Toronto FC

FC Dallas Nashville SC

American Major League Soccer

2026-03-01T01:30:00+00:00

Both Teams to Score

FC Dallas Nashville SC

Houston Dynamo Los Angeles FC

American Major League Soccer

2026-03-01T01:30:00+00:00

Both Teams to Score

Houston Dynamo Los Angeles FC

Austin FC DC United

American Major League Soccer

2026-03-01T19:30:00+00:00

Over/Under Goals

Austin FC DC United

Real Salt Lake Seattle Sounders

American Major League Soccer

2026-03-01T00:30:00+00:00

Over/Under Goals

Real Salt Lake Seattle Sounders

Colorado Rapids Portland Timbers

American Major League Soccer

2026-02-28T21:30:00+00:00

Over/Under Goals

Colorado Rapids Portland Timbers

Chicago Fire CF Montréal

American Major League Soccer

2026-02-28T19:30:00+00:00

Over/Under Goals

Chicago Fire CF Montréal

Minnesota United FC Cincinnati

American Major League Soccer

2026-02-28T21:30:00+00:00

Over/Under Goals

Minnesota United FC Cincinnati

New York Red Bulls New England Revolution

American Major League Soccer

2026-02-28T19:30:00+00:00

Over/Under Goals

New York Red Bulls New England Revolution

Seattle Sounders Colorado Rapids

American Major League Soccer

2026-02-23T02:15:00+00:00

Over/Under Goals

Seattle Sounders Colorado Rapids

LA Galaxy New York City FC

American Major League Soccer

2026-02-23T00:00:00+00:00

Over/Under Goals

LA Galaxy New York City FC

Houston Dynamo Chicago Fire

American Major League Soccer

2026-02-22T01:30:00+00:00

Over/Under Goals

Houston Dynamo Chicago Fire

Orlando City New York Red Bulls

American Major League Soccer

2026-02-22T00:30:00+00:00

Over/Under Goals

Orlando City New York Red Bulls

San Jose Earthquakes Sporting Kansas City

American Major League Soccer

2026-02-22T03:30:00+00:00

Over/Under Goals

San Jose Earthquakes Sporting Kansas City

San Diego FC CF Montréal

American Major League Soccer

2026-02-22T03:30:00+00:00

Moneyline (1X2)

San Diego FC CF Montréal

Portland Timbers Columbus Crew

American Major League Soccer

2026-02-22T03:30:00+00:00

Over/Under Goals

Portland Timbers Columbus Crew

Los Angeles FC Inter Miami

American Major League Soccer

2026-02-22T02:30:00+00:00

Over/Under Goals

Los Angeles FC Inter Miami

Nashville SC New England Revolution

American Major League Soccer

2026-02-22T01:30:00+00:00

Both Teams to Score

Nashville SC New England Revolution

FC Dallas Toronto FC

American Major League Soccer

2026-02-22T01:30:00+00:00

Over/Under Goals

FC Dallas Toronto FC

Austin FC Minnesota United

American Major League Soccer

2026-02-22T01:30:00+00:00

Over/Under Goals

Austin FC Minnesota United

Vancouver Whitecaps Real Salt Lake

American Major League Soccer

2026-02-22T00:30:00+00:00

Over/Under Goals

Vancouver Whitecaps Real Salt Lake

DC United Philadelphia Union

American Major League Soccer

2026-02-22T00:30:00+00:00

Both Teams to Score

DC United Philadelphia Union